Non Hodgkins Lymphoma

Non Hodgkins lymphoma is a cancer type affecting white blood cells known as lymphocytes, whose role is to protect the body against various infections. Non hodgkins lymphoma is a collection of 30 or additional cancer commencing in the lymphocytes; however, all of them are similar in some ways though they differ depending on how they occur. They are all known as non-Hodgkin lymphoma to differentiate them from Hodgkins lymphoma, another tumor of the lymphocytes.



Many people suffering from non hodgkins lymphoma do not detect any symptoms. Their infection may be established during a regular physical assessment or a check for a different health problem. When people become aware of the symptoms of lymphoma, an enlarged lymph node is one of the most common symptoms. Other symptoms may arise due to growth of cancer cells. These symptoms vary based upon the location at which the tumor is growing. For example, a patient may experience indigestion or stomach pain if a cancer develops near or in the stomach. Other common non Hodgkins lymphoma symptoms include:

• Fever

• Night sweats

• Unexplained weight loss

• Extreme tiredness or fatigue

• Loss of appetite

• Very itchy skin

These symptoms of non hodgkin lymphoma can as well be signs of other illnesses. If the above symptoms are observed, it is highly recommendable to visit a doctor for further diagnosis.



Chemotherapy: this active treatment has been in use for quite a long duration for lymphatic cancers whose main aim is to slow down the spreading of non hodgkin lymphoma hence inhibiting their growth. Chemotherapy differs based on the severity of the tumor form example:

Chemotherapy for indolent lymphoma. For indolent lymphomas, this type of therapy often brings a reduction, but degeneration (recurrence of the ailment) is frequent. At relapse, a physician may advise repeated chemotherapy or use of a different treatment option, e.g. immunotherapy or transplant. For some patients, repetitive relapses can be dealt with using chemotherapy for a prolonged duration.

However, in some patients diagnosed with indolent lymphoma experience an extended reduction with chemotherapy only. Over time, non Hodgkins lymphoma may build up into an antagonistic form of lymphoma, which may call for other effective treatments such as a cord blood transplant or bone marrow.

Chemotherapy for aggressive lymphomas: aggressive lymphomas require the use of various combinations of chemotherapy drugs, which can also be used in conjunction with immunotherapy known as monoclonal antibody therapy. In case the central nervous system of the patient has been infected or there is a likelihood of infections occurring, chemotherapy injections can be administered into the fluid surrounding the spinal cord.

Immunotherapy: immunotherapy or biological therapy focuses on the use of immune system as a defense mechanism against infections. Immunotherapy for non Hodgkin lymphoma includes:

Monoclonal antibody therapy: the most immunotherapy used for non hodgkin lymphoma is rituximab, laboratory-made a monoclonal antibody. The role of monoclonal antibodies is to mark specific cell types for attack by the patient`s immune system.

Monoclonal antibodies with radiation: this therapy is also known as radioimmunotherapy and uses monoclonal antibodies for transportation of radiation to the cancer cells directly. This makes the tumor cells to receive direct radiation hence leading to their destruction.

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